In this Post How to Delete Registration Form with Profile Image Asp.Net

Important Namespaces Used
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using System.Data;
using System.Data.SqlClient;

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Static Variable Declaration
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 static String imagelink;

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Search Button Click Event
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String mycon = "Data Source=sk-pc; Initial Catalog=Class-College-Database; Integrated Security=True";
        String myquery = "Select * from profiledetail where rollno=" + TextBox1.Text;
        SqlConnection con = new SqlConnection(mycon);
        SqlCommand cmd = new SqlCommand();
        cmd.CommandText = myquery;
        cmd.Connection = con;
        SqlDataAdapter da = new SqlDataAdapter();
        da.SelectCommand = cmd;
        DataSet ds = new DataSet();
        da.Fill(ds);
        if (ds.Tables[0].Rows.Count > 0)
        {
            Label4.Text = "Particular Roll Number Found";
            TextBox2.Text = ds.Tables[0].Rows[0]["sname"].ToString();
            TextBox3.Text = ds.Tables[0].Rows[0]["fname"].ToString();
            TextBox4.Text = ds.Tables[0].Rows[0]["mname"].ToString();
            imagelink = ds.Tables[0].Rows[0]["profileimage"].ToString();
            Image1.ImageUrl = imagelink+ "?n=" + DateTime.Now.Second.ToString();
            
        }
        else
        {
            Label4.Text = "Particular Roll Number Not Found";

        }
        con.Close();

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Delete Button Click Event Coding
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String mycon = "Data Source=sk-pc; Initial Catalog=Class-College-Database; Integrated Security=True";
        String updatedata = "delete from profiledetail where rollno=" + TextBox1.Text;
        SqlConnection con = new SqlConnection(mycon);
        con.Open();
        SqlCommand cmd = new SqlCommand();
        cmd.CommandText = updatedata;
        cmd.Connection = con;
        cmd.ExecuteNonQuery();
        Label5.Text = "Particular Searched Rollno Has Been Deleted";
        System.IO.File.Delete(Server.MapPath(imagelink));

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